Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00994)
MIC Name Plesiomonas shigelloides (enterobacteria)
MIC Synonyms Pseudomonas shigelloides
Body Site Blood
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Plesiomonas
Species: Plesiomonas shigelloides
Oxygen Sensitivity Facultative anaerobe
Microbial Metabolism Respiratory
Gram Negative
Host Relationship Opportunistic pathogen
Genome Size (bp) 3405979
No. of Coding Genes 29
No. of Non-Coding Genes 147
No. of Small Non-Coding Genes 147
No. of Gene Transcripts 3057
No. of Base Pairs 3405979
Description Plesiomonas shigelloides (formerly known Aeromonas shigelloides) is anfacultatively anaerobic, Gram-negative, oxidase-positive, rod-shaped bacterium which has been isolated from freshwater, freshwater fish, and shellfish and from many types of animals including humans, cattle, goats, swine, cats, dogs, monkeys, vultures, snakes, and toads. It has emerged as a cause of enteric disease in humans, especially following the consumption of raw seafood.
External Links Taxonomy ID
703
Genome Assembly ID
31289_E01
GOLD Organism ID
Go0041498
Disease Relevance
          Irritable bowel syndrome  [ICD-11: DD91]
             Description Plesiomonas shigelloides was associated with Diarrheal disease. [1]
Host Immune Factors (HIFs)
          Interleukin-1 beta
             HIF ID HIFM0138 HIF Info       Class Cytokine (Cyt)
             Description The biological activities of Plesiomonas shigelloides lipid A can induce the productions of proinflammatory cytokines IL-1beta. [2]
          Interferon-6
             HIF ID HIFM0151 HIF Info       Class Cytokine (Cyt)
             Description The biological activities of Plesiomonas shigelloides lipid A can induce the productions of proinflammatory cytokines IL-6. [2]
          Tumor necrosis factor
             HIF ID HIFM0226 HIF Info       Class Cytokine (Cyt)
             Description Plesiomonas shigelloides could induce the production of proinflammatory cytokines (TNF-Aloha, IL-1Beta, and IL-6). [2]
          Macrophages
             HIF ID HIFC0020 HIF Info       Class Macrophages (Mac)
             Description The heptaacylated form of Plesiomonas shigelloides lipid A(LA) exhibited strong effect on proinflammatory activity, significantly decreasing the levels of all tested cytokines in human macrophages. [2]
          Toll-like receptor 4
             HIF ID HIFM0219 HIF Info       Class Toll-like receptor (TLR)
             Description Plesiomonas shigelloides could Stimulate the production of the proinflammatory cytokine TNF- (A) and IL-6 (B) by TLR4 / murine macrophages. [2]
References
1 Intestinal secretory immune response to infection with Aeromonas species and Plesiomonas shigelloides among students from the United States in Mexico. J Infect Dis. 1991 Nov;164(5):979-82. doi: 10.1093/infdis/164.5.979.
2 Structure-Activity Relationship of Plesiomonas shigelloides Lipid A to the Production of TNF-, IL-1, and IL-6 by Human and Murine Macrophages. Front Immunol. 2017 Dec 11;8:1741. doi: 10.3389/fimmu.2017.01741. eCollection 2017.

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