Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01018)
MIC Name Prevotella nanceiensis (CFB bacteria)
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Prevotellaceae
Genus: Prevotella
Species: Prevotella nanceiensis
Oxygen Sensitivity Anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Negative
Host Relationship Commensal
Genome Size (bp) 2648555
Description Prevotella nanceiensis is an anaerobic, Gram negative bacterium. In a study ,the saliva of T-CD children showed the largest amount of Bacteroidetes, eg. Prevotella nanceiensis.
External Links Taxonomy ID
425941
Genome Assembly ID
ASM37996v1
GOLD Organism ID
Go0092048
Disease Relevance
          Coeliac disease  [ICD-11: DA95]
             Description The largest amount of Prevotella nanceiensis showed in the saliva of T-celiac disease children. [1]
Host Immune Factors (HIFs)
          C-C motif chemokine 20
             HIF ID HIFM0023 HIF Info       Class Cytokine (Cyt)
             Description Prevotella nanceiensis can increased levels of CCL20 expression to induce severe lung neutrophilia in mice. [2]
          Interleukin-1 beta
             HIF ID HIFM0138 HIF Info       Class Cytokine (Cyt)
             Description Prevotella nanceiensis in the vaginal microbiota was associated with increased innate IL1beta cytokines. [2]
          C-X-C motif chemokine 8
             HIF ID HIFM0153 HIF Info       Class Cytokine (Cyt)
             Description Prevotella nanceiensis could decrease the expression of IL-8. [2]
          Immunoglobulin A
             HIF ID HIFM0272 HIF Info       Class Immunoglobulin (Ig)
             Description Prevotella nanceiensis is positively associated with IgA. [3]
          Toll-like receptor 2
             HIF ID HIFM0217 HIF Info       Class Toll-like receptor (TLR)
             Description The diminished lung inflammatory capacity of Prevotella nanceiensis was dependent on TLR2. [2]
Environmental Factor(s)
             Disbiome ID
      436
             gutMDisorder ID
      gm0535
References
1 Salivary microbiota and metabolome associated with celiac disease. Appl Environ Microbiol. 2014 Jun;80(11):3416-25. doi: 10.1128/AEM.00362-14. Epub 2014 Mar 21.
2 The immune response to Prevotella bacteria in chronic inflammatory disease. Immunology. 2017 Aug;151(4):363-374. doi: 10.1111/imm.12760. Epub 2017 Jun 20.
3 Oral microbiota dysbiosis and its association with Henoch-Schnlein Purpura in children.Int Immunopharmacol. 2018 Dec;65:295-302. doi: 10.1016/j.intimp.2018.10.017. Epub 2018 Oct 17.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.