Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01402)
MIC Name Yersinia pseudotuberculosis (enterobacteria)
MIC Synonyms Bacterium pseudotuberculosis
Body Site Skin
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Yersiniaceae
Genus: Yersinia
Species: Yersinia pseudotuberculosis
Oxygen Sensitivity Facultative anaerobe
Microbial Metabolism Fermentative; Respiratory
Gram Negative
Genome Size (bp) 4806594
No. of Coding Genes 4113
No. of Non-Coding Genes 103
No. of Small Non-Coding Genes 103
No. of Gene Transcripts 4216
No. of Base Pairs 4806594
Description Yersinia pseudotuberculosis is a facultatively anaerobic, Gram negative bacterium. It causes Far East scarlet-like fever in humans.
External Links Taxonomy ID
633
Genome Assembly ID
ASM75031v1
GOLD Organism ID
Go0003357
Disease Relevance
          Far East scarlet-like fever  [ICD-11: 1B9A]
             Description Far East Scarlet-Like Fever Caused by a Few Related Genotypes of Yersinia pseudotuberculosis. [1]
Host Immune Factors (HIFs)
          Regenerating islet-derived protein 3-beta
             HIF ID HIFM0197 HIF Info       Class Antimicrobial peptide (AMP)
             Description The impaired clearance of Yersinia pseudotuberculosis in vivo may cause the approximately 2-fold decrease of Reg3b expression in Tlr2-deficient mice. [2]
          B cells
             HIF ID HIFC0001 HIF Info       Class B cells (BCs)
             Description The increased activation of CD4+ T cell may induce a progressive serum antibody to response to Yersinia pseudotuberculosis, which provided help to B cells. [3]
          Immunoglobulin Y
             HIF ID HIFM0274 HIF Info       Class Immunoglobulin (Ig)
             Description Our data suggest that IMs differentiate into DCs in MLN pyogranulomas and direct adaptive responses in T cells at the expense of innateimmunity during oral Y.pseudotuberculosis infection. [3]
          CD4+ regulatory T cells
             HIF ID HIFC0034 HIF Info       Class T cells (TCs)
             Description CD4+ T cell numbers was reduced in the absence of CCR2 during Yersinia pseudotuberculosis infection. [3]
          CD8+ T cells
             HIF ID HIFC0073 HIF Info       Class T cells (TCs)
             Description Yersinia pseudotuberculosis is associated with CD8+ T cells responses. [3]
Environmental Factor(s)
             Disbiome ID
      1094
References
1 Far East Scarlet-Like Fever Caused by a Few Related Genotypes of Yersinia pseudotuberculosis, Russia. Emerg Infect Dis. 2016 Mar;22(3):503-6. doi: 10.3201/eid2203.150552.
2 Salmonella-induced mucosal lectin RegIII kills competing gut microbiota.PLoS One. 2011;6(6):e20749. doi: 10.1371/journal.pone.0020749. Epub 2011 Jun 9.
3 CCR2(+) Inflammatory Monocytes Are Recruited to Yersinia pseudotuberculosis Pyogranulomas and Dictate Adaptive Responses at the Expense of Innate Immunity during Oral Infection. Infect Immun. 2018 Feb 20;86(3):e00782-17. doi: 10.1128/IAI.00782-17. Print 2018 Mar.

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