General Information of HGF (ID: HGF2331)
HGF Name MUC2
HGF Synonym(s) MLP, SMUC, MUC-2, mucin 2, oligomeric mucus/gel-forming
Source Homo sapiens
HGF Classification Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location chr11
Gene Start Site 1074875 Gene End Site 1110511
Strand Forward (+)
External Links
Ensembl ID
ENSG00000198788
Microbe Species (MIC) Regulated by This HGF
         Akkermansia muciniphila (verrucomicrobia) MIC00056
             Description The deletion of MUC2 increased the abundance of Akkermansia municiphila. [1]
         Bacteroidetes (CFB bacteria) MIC00141
             Description The deletion of MUC2 has been associated with the decreased amount of Bacteroidetes. [2]
         Desulfovibrio sp. (delta-proteobacteria) MIC00493
             Description The deletion of MUC2 showed increased abundance of Desulfovibrio. [1]
         Erysipelothrix rhusiopathiae (firmicutes) MIC00559
             Description The deletion of MUC2 showed significantly increased abundance of Erysipelotrichaceae (p-value<0.05). [1]
         Escherichia coli (enterobacteria) MIC00516
             Description The deletion of MUC2 was significantly increased the abundance of Escherichia coli (p-value<0.05). [1]
         Lachnospiraceae (firmicutes) MIC00695
             Description The deletion of MUC2 showed significantly decreased abundance of Lachnospiraceae (p-value<0.05). [1]
         Lactobacillus sp. (firmicutes) MIC00701
             Description The deletion of MUC2 showed decreased abundance of Lactobacilli. [1]
         Marvinbryantia formatexigens (firmicutes) MIC01416
             Description The deletion of MUC2 was significantly increased the abundance of Marvinbryantia (p-value<0.05). [1]
         Ruminococcus sp. (firmicutes) MIC01140
             Description The deletion of MUC2 showed significantly increased abundance of Ruminococcaceae (p-value<0.05). [1]
         Turicibacter (firmicutes) MIC01339
             Description The deletion of MUC2 showed increased abundance of Turicibacter. [1]
References
1 The Dynamic Changes of Gut Microbiota in Muc2 Deficient Mice.Int J Mol Sci. 2018 Sep 18;19(9):2809. doi: 10.3390/ijms19092809.
2 Current understanding of the gut microbiota shaping mechanisms.J Biomed Sci. 2019 Aug 21;26(1):59. doi: 10.1186/s12929-019-0554-5.

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