Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00888)
MIC Name Neisseria lactamica (beta-proteobacteria)
MIC Synonyms Neisseria lactamicus
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Neisseriales
Family: Neisseriaceae
Genus: Neisseria
Species: Neisseria lactamica
Oxygen Sensitivity Facultative anaerobe
Microbial Metabolism Saccharolytic; Respiratory or Fermentative
Gram Negative
Description Neisseria lactamica is a Gram-negative diplococcus bacterium. It is strictly a commensal species of the nasopharynx.
External Links Taxonomy ID
486
Genome Assembly ID
ASM17399v1
GOLD Organism ID
Go0507372
Host Immune Factors (HIFs)
          Interferon-10
             HIF ID HIFM0128 HIF Info       Class Cytokine (Cyt)
             Description Neisseria lactamica infection increases the IL-10 expression. [1]
          Interferon-12 subunit alpha
             HIF ID HIFM0130 HIF Info       Class Cytokine (Cyt)
             Description Neisseria lactamica increased the IL-12 expression. [1]
          Interferon-4
             HIF ID HIFM0149 HIF Info       Class Cytokine (Cyt)
             Description Neisseria lactamica PorB can increase the secretion of cytokines IL-4. [1]
          Interferon gamma
             HIF ID HIFM0260 HIF Info       Class Cytokine (Cyt)
             Description The Th1 cytokines INF-Gamma and IL-12p70 were also augmented in response to Neisseria lactamica PorB. [1]
          Immunoglobulin G2
             HIF ID HIFM0268 HIF Info       Class Immunoglobulin (Ig)
             Description Neisseria lactamica was associated with IgG2 response. [1]
          Immunoglobulin G1
             HIF ID HIFM0269 HIF Info       Class Immunoglobulin (Ig)
             Description Significantly higher titers (p = < 0.05) of OVA-specific IgG1 were induced by alum and by Neisseria lactamica PorB as compared to OVA alone. [1]
Environmental Factor(s)
             Disbiome ID
      1129
             gutMDisorder ID
      gm0466
References
1 The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant. Vaccine. 2008 Feb 6;26(6):786-96. doi: 10.1016/j.vaccine.2007.11.080. Epub 2007 Dec 26.

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