| General Information of MIC (ID: MIC01369) |
| MIC Name |
Vibrio cholerae (gamma-proteobacteria)
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| MIC Synonyms |
Vibrio cholera
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| Body Site |
Lung
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| Lineage |
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Vibrionales
Family: Vibrionaceae
Genus: Vibrio
Species: Vibrio cholerae
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| Oxygen Sensitivity |
Facultative anaerobe
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| Microbial Metabolism |
Fermentative; Respiratory
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| Gram |
Negative
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| Host Relationship |
Pathogen
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| Genome Size (bp) |
4012216
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| No. of Coding Genes |
3585
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| No. of Non-Coding Genes |
77
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| No. of Small Non-Coding Genes |
77
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| No. of Gene Transcripts |
3662
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| No. of Base Pairs |
4012216
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| Description |
Vibrio cholerae is a facultative anaerobic, Gram-negative, comma-shaped bacterium. Some strains of V. cholerae cause the disease cholera, which can be derived from the consumption of undercooked or raw marine life species. V. cholerae can undergo respiratory and fermentative metabolism.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Immune Factors (HIFs) |
| B cells |
| HIF ID |
HIFC0001 |
HIF Info
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Class |
B cells (BCs) |
| Description |
Vibrio cholerae O antigen responses in patients recovering from cholera are characterized by high levels of cross-reactive recall responses of memory B cells from prior antigen exposure. |
[1] |
| IgA plasma B cell |
| HIF ID |
HIFC0221 |
HIF Info
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Class |
B cells (BCs) |
| Description |
Anti-OSP(O-specific polysaccharide) IgA plasma cell responses significantly happened following the first vaccination against killed Vibrio cholerae O1 and O139 organisms. |
[2] |
| Immunoglobulin M |
| HIF ID |
HIFM0266 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Vibrio choleraeis was associated with IgM response. |
[1] |
| Immunoglobulin G1 |
| HIF ID |
HIFM0269 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Vibrio cholerae was associated with IgG1 response. |
[3] |
| Immunoglobulin G |
| HIF ID |
HIFM0270 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Vibrio choleraeis was associated with IgM response. |
[1] |
| Immunoglobulin A |
| HIF ID |
HIFM0272 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Vibrio choleraeis was associated with IgA response. |
[1] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| aBiofilm Organism |
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| References |
| 1 |
Vibrio cholerae at the Intersection of Immunity and the Microbiome. mSphere. 2019 Nov 27;4(6):e00597-19. doi: 10.1128/mSphere.00597-19.
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| 2 |
Immune responses to O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 Ogawa in adult Bangladeshi recipients of an oral killed cholera vaccine and comparison to responses in patients with cholera.Am J Trop Med Hyg. 2014 May;90(5):873-81. doi: 10.4269/ajtmh.13-0498. Epub 2014 Mar 31.
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| 3 |
Plant-based production of two chimeric monoclonal IgG antibodies directed against immunodominant epitopes of Vibrio cholerae lipopolysaccharide.J Immunol Methods. 2015 Jul;422:111-7. doi: 10.1016/j.jim.2015.04.001. Epub 2015 Apr 9.
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