Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01410)
MIC Name Lactobacillus helveticus (firmicutes)
MIC Synonyms Thermobacterium helveticum
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus helveticus
Oxygen Sensitivity Facultative anaerobe
Microbial Metabolism Saccharolytic; Respiratory or Fermentative
Gram Positive
Host Relationship Probiotic
Genome Size (bp) 2080931
Description Lactobacillus helveticus is a lactic-acid producing, rod-shaped bacterium of the genus Lactobacillus. This bacterium is also used as probiotic.
External Links Taxonomy ID
1587
Genome Assembly ID
ASM76546v1
GOLD Organism ID
Go0001532
Host Immune Factors (HIFs)
          B cells
             HIF ID HIFC0001 HIF Info       Class B cells (BCs)
             Description Lactobacillus helveticus SBT2171 could stimulate B cells resopnses. [1]
          Interleukin-1 beta
             HIF ID HIFM0138 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus helveticus OFS 1515 alleviated proinflammatory cytokines IL-1Beta. [2]
          Interferon-4
             HIF ID HIFM0149 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus helveticus OFS 1515 alleviated proinflammatory cytokines IL-1Beta. [2]
          Tumor necrosis factor
             HIF ID HIFM0226 HIF Info       Class Cytokine (Cyt)
             Description Nevertheless, all three strains Lactobacillus paracasei OFS 0291, Lactobacillus helveticus OFS 1515 andLactobacillus fermentum DR9 alleviated proinflammatory cytokines TNF-Alpha, IFN-Gamma and IL-1Beta as well as IL-4, the Thelper (Th) 2 cell promoter in the gut. [2]
          Interferon gamma
             HIF ID HIFM0260 HIF Info       Class Cytokine (Cyt)
             Description Nevertheless, all three strains Lactobacillus paracasei OFS 0291, Lactobacillus helveticus OFS 1515 andLactobacillus fermentum DR9 alleviated proinflammatory cytokines TNF-Alpha, IFN-Gamma and IL-1Beta as well as IL-4, the Thelper (Th) 2 cell promoter in the gut. [2]
          T helper type 2 cells
             HIF ID HIFC0085 HIF Info       Class T cells (TCs)
             Description Lactobacillus helveticus OFS 1515 alleviated proinflammatory cytokines TNF-, IFN- and IL-1 as well as IL-4 produced by Th2 cells. [2]
Environmental Factor(s)
             Disbiome ID
      1570
             gutMDisorder ID
      gm0393
References
1 Cutting Edge: Probiotics and Fecal Microbiota Transplantation in Immunomodulation.J Immunol Res. 2019 Apr 16;2019:1603758. doi: 10.1155/2019/1603758. eCollection 2019.
2 Lactobacillus sp. improved microbiota and metabolite profiles of aging rats. Pharmacol Res. 2019 Aug;146:104312. doi: 10.1016/j.phrs.2019.104312. Epub 2019 Jun 14.

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