Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00723)
MIC Name Lactobacillus kefiranofaciens (firmicutes)
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus kefiranofaciens
Oxygen Sensitivity Anaerobe
Microbial Metabolism Saccharolytic
Gram Positive
Genome Size (bp) 2354088
Description Lactobacillus kefiranofaciens is an anaerobic, Gram positive, non-pathogenic bacterium.
External Links Taxonomy ID
267818
Genome Assembly ID
ASM21478v1
GOLD Organism ID
Go0544000
Disease Relevance
          Vibrio mimicus gastroenteritis  [ICD-11: 1A40]
             Description Lactobacillus kefiranofaciens had anti-colitis abilities in a number of in-vitro and in-vivo experiments. [1]
Host Immune Factors (HIFs)
          Interferon-10
             HIF ID HIFM0128 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus kefiranofaciens may slightly increased the IL-10 expression. [2]
          Interferon-12 subunit alpha
             HIF ID HIFM0130 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus kefiranofaciens could induce the IL-12 expression. [2]
          Interferon-4
             HIF ID HIFM0149 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus kefiranofaciens could induce IL-4 expression. [2]
          Interferon-6
             HIF ID HIFM0151 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus kefiranofaciens could induce the IL-6 expression. [2]
          Tumor necrosis factor
             HIF ID HIFM0226 HIF Info       Class Cytokine (Cyt)
             Description the abundance of Lactobacillus kefiranofaciens may be associated with TNFAlpha. [2]
          Interferon gamma
             HIF ID HIFM0260 HIF Info       Class Cytokine (Cyt)
             Description The abundance of Lactobacillus kefiranofaciens may be associated with IFN-Gamma. [2]
          Immunoglobulin G
             HIF ID HIFM0270 HIF Info       Class Immunoglobulin (Ig)
             Description The abundance of Lactobacillus kefiranofaciens is associated with IgG. [2]
          Immunoglobulin A
             HIF ID HIFM0272 HIF Info       Class Immunoglobulin (Ig)
             Description The abundance of Lactobacillus kefiranofaciens is associated with IgA. [2]
Environmental Factor(s)
             Disbiome ID
      1
             gutMDisorder ID
      gm0393
References
1 Effects of Lactobacillus kefiranofaciens M1 isolated from kefir grains on germ-free mice. PLoS One. 2013 Nov 11;8(11):e78789. doi: 10.1371/journal.pone.0078789. eCollection 2013.
2 Effects of the oral administration of the exopolysaccharide produced by Lactobacillus kefiranofaciens on the gut mucosal immunity. Cytokine. 2006 Dec;36(5-6):254-60. doi: 10.1016/j.cyto.2007.01.003. Epub 2007 Mar 23.

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