Details of Host Genetic Factor (HGF) Regulating Microbe Species (MIC)

General Information of HGF (ID: HGF2348)
HGF Name C4B
HGF Synonym(s) CH, C4F, CO4, C4B1, C4B2, C4B3, C4B5, C4BD, C4B12, C4B_2, CPAMD3, complement C4B
Source Homo sapiens
HGF Classification Copy Number Variation: Gene Duplication (CNV-GDu)
Gene Location chr6
Gene Start Site 32014795 Gene End Site 32035418
Strand Forward (+)
External Links
Ensembl ID
ENSG00000224389
Microbe Species (MIC) Regulated by This HGF
         Collinsella stercoris (actinobacteria) MIC00435
             Description The low C4B-CN has been significantly associated with the abundance of Collinsella (p-value<0.05). [1]
         Enterococcus sp. (firmicutes) MIC00552
             Description The low C4B-CN has been significantly associated with the decreased abundance of Enterococcus (p-value<0.05). [1]
         Erysipelatoclostridium ramosum (firmicutes) MIC00414
             Description The low C4B-CN has been significantly associated with the abundance of Clostridium ramosum (p-value<0.05). [1]
         Escherichia coli (enterobacteria) MIC00516
             Description The low C4B-CN has been significantly associated with the decreased abundance of Escherichia coli (p-value<0.05). [1]
         Eubacterium rectale (firmicutes) MIC00578
             Description The low C4B-CN has been significantly associated with the high abundance of Eubacterium rectale (p-value<0.05). [1]
         Eubacterium sp. (firmicutes) MIC00581
             Description The low C4B-CN has been significantly associated with the high abundance of Eubacterium (p-value<0.05). [1]
         Eubacterium ventriosum (firmicutes) MIC00583
             Description The low C4B-CN has been significantly associated with the high abundance of Eubacterium ventriosum (p-value<0.05). [1]
         Holdemanella biformis (firmicutes) MIC00572
             Description The low C4B-CN has been significantly associated with the high abundance of Eubacterium biforme (p-value<0.05). [1]
         Klebsiella pneumoniae (enterobacteria) MIC01405
             Description The low C4B-CN has been significantly associated with the decreased abundance of Klebsiella pneumoniae (p-value<0.05). [1]
         Klebsiella sp. (enterobacteria) MIC00688
             Description The low C4B-CN has been significantly associated with the decreased abundance of Klebsiella (p-value<0.05). [1]
         Lachnospira pectinoschiza (firmicutes) MIC01956
             Description The low C4B-CN has been significantly associated with the high abundance of Lachnospira pectinoschiza (p-value<0.05). [1]
         Ruminococcus callidus (firmicutes) MIC01134
             Description The low C4B-CN has been significantly associated with the high abundance of Ruminococcus (p-value<0.05). [1]
         Ruminococcus sp. (firmicutes) MIC01140
             Description The low C4B-CN has been significantly associated with the high abundance of Ruminococcus (p-value<0.05). [1]
         Serratia fonticola (enterobacteria) MIC01169
             Description The low C4B-CN has been significantly associated with the decreased abundance of Serratia (p-value<0.05). [1]
References
1 C4B gene influences intestinal microbiota through complement activation in patients with paediatric-onset inflammatory bowel disease.Clin Exp Immunol. 2017 Dec;190(3):394-405. doi: 10.1111/cei.13040. Epub 2017 Sep 25.

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